Hematology is the science or study of blood and blood diseases.

Hematology is the science or study of blood and blood diseases, and it is frequently associated with oncology. 

In the medical field, hematology includes the treatment of blood disorders and malignancies, including types of hemophilia, blood clots, leukemia, lymphoma, myeloma and sickle-cell anemia. Hematology is a branch of internal medicine that deals with the physiology, pathology, etiology, diagnosis, treatment, prognosis and prevention of blood-related disorders.

Hematologists focus largely on lymphatic systems and bone marrow and may diagnose blood count irregularities or platelet irregularities. Hematologists treat organs that are fed by blood cells, including the lymph nodes, spleen, thymus and lymphoid tissue.

Blood is made up of several parts, including red blood cells, white blood cells and platelets (combined, about 45% of volume) as well as plasma (about 55% of volume). Red blood cells (also known as RBCs or erythrocytes), which make up about 45% of whole blood, carry oxygen from the lungs to the body’s tissue. They also carry carbon dioxide back to the lungs to be exhaled. They are disc-shaped and produced in the bone marrow.

White blood cells (also known as WBCs or leukocytes), which are also made in the marrow, help fight infection. Together with platelets, they make up less than 1% of whole blood. Platelets (also called thrombocytes) are small, colorless fragments that stick together and interact with clotting proteins to stop or prevent bleeding. They are also produced in bone marrow.

Plasma is the yellowish fluid part of the blood. Composed of 92% water, it also contains 7% vital proteins and 1% mineral salts, sugars, fats, hormones and vitamins.

Four major areas of study within hematology include hemoglobinopathy, hematologic malignancies, anemia and coagulopathy. Hemoglobinopathy is the study of abnormality in the globin chains of hemoglobin molecules. In addition to sickle cell anemia, thalassemia (also known as erythropoiesis) is part of hemoglobinopathy.

The area of hematologic malignancies is concerned with the diagnosis and treatment of cancers of the bone marrow, blood and lymph nodes. Myeloma is one type of hematologic malignancy, along with leukemia and lymphoma. Other disorders treated by a hematologist include arterial thromboembolism, deep-vein thrombosis and neutropenia.

Although hematologists work together with experts from various medical and surgical specialties, hematology is most often linked with oncology. Hematologists and oncologists work together to care for adults and children with cancers of the blood and bone marrow, including leukemia and lymphoma.

One of the most common hematology tests is the complete blood count, or CBC. This test is often conducted during a routine exam and can detect anemia, clotting problems, blood cancers, immune system disorders and infections. 

Other hematology tests include:

  • Blood chemistry test;
  • Blood enzyme test; and
  • Blood tests to assess heart disease risk.

When something is wrong with your blood, it can affect your total health. That is why it is important for you to know about some of the common blood disorders that may affect you. Blood diseases affect millions of people each year. These inherited and acquired diseases, including the anemias, venous thromboembolism, hemophilia, and other bleeding disorders, can affect red and white blood cells, platelets, bone marrow, vascular endothelium, or plasma proteins. These conditions can cause blood cells to function abnormally, which may lead to disease or affect overall health.

People may be affected by many different types of blood conditions and blood cancers. Common blood disorders include anemia, bleeding disorders such as hemophilia, blood clots, and blood cancers such as leukemia, lymphoma, and myeloma.

Talking to your doctor is the first step to take if you believe you may have a blood condition. If you are diagnosed with a blood disorder, your doctor may refer you to a hematologist.

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